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Commonly Used Peptides

DSIP (Delta Sleep-Inducing Peptide)

During delta sleep, growth hormone and IGF-1 are secreted. They are the hormones responsible for stem cell regeneration and cellular reparative processes. DSIP (Delta Sleep-Inducing Peptide) is a peptide that induces delta sleep within hours of falling asleep and contributes to the mentioned reparative processes in our body.

MOTS-C

MOTS-C is a unique peptide that has been scientifically shown to improve mitochondrial biogenesis. The mitochondria exist in every human cell, including stem cells; it’s the power plant of each cell. If the mitochondria are functioning inefficiently, the cell is unable to regenerate. Mitochondria biogenesis is essential for life.

BPC 157, CJC 1295, Ipamorelin, and IGF-1

These peptides can promote hormone growth and repair damaged tissues in the bones, ligaments, joints, and connective tissue. They do this by instructing the cells in skeletal muscle, bone, cartilage, fibroblasts, as well as heart and lung tissue to regenerate. These peptide therapies can also expand lean muscle mass to prevent sarcopenia (loss of muscle tissue).

Hexarelin

Hexarelin is a peptide that reduces fat mass while expanding lean muscle mass and stimulating the body’s growth hormone. It also protects the heart muscle with a cardioprotective effect and can regenerate stem cells.

AOD 9064

AOD 9064 is a peptide that works to melt away body fat stored within the abdomen that can cause inflammation and ongoing oxidation. This peptide can reduce the fatty issue and, therefore, prevent the body from developing the following diseases:

  • Type 2 diabetes
  • Cancer
  • Obesity
  • Dementia
  • Alzheimer’s disease

Melanotan II

Melanotan II is a peptide that stimulates fat loss and growth hormone release while also increasing libido or sex drive in both men and women. It can also enhance skin pigmentation.

Bremelanotide PT 141

Bremelanotide PT 141 is a highly specific peptide that addresses erectile dysfunction and enhances libido (sex drive) in both men and women. This peptide crosses the blood-brain barrier, bypassing the vascular system and acting directly on the central nervous system to improve erectile dysfunction. Bremelanotide PT 141 can be taken orally or as a nasal spray, making its use convenient and discreet.

Follistatin 344 & 315

Follistatin 344 and 315 are peptides that inhibit muscle myostatin, which prevents muscles from growing; follistatin blocks the action of myostatin so muscles may grow in size. Lean muscle mass is essential for a healthy metabolism. Without muscle mass, people would waste away and expose themselves to multiple disease states like insulin resistance, sarcopenia, heart and lung failure, as well as dementia and stroke.

Cerebrolysin

A nootropic, neuroprotective, neuroregenerative neuropeptide effective in improving cognitive function, memory, attention, focus, speed, creativity and mental flexibility in people with mild to moderately severe Alzheimer’s disease, following organic or vascular dementia, after traumatic brain injury from any cause, including concussion from either boxing or MMA fighting or any other sports competition like football, soccer or basketball.

People who have suffered a recent stroke have benefited from Cerebrolysin with an improvement in cognition and “quality of life” measures in many clinical studies.

Cerebrolysin is effective in regenerating and protecting axons and dendrites not only in the brain, but also in the spinal cord to improve synaptic function. When synaptic function in the brain is regenerated, memory and cognitive abilities return as long as there isn’t any permanent damage following a stroke.

Thymosin Alpha-1

Thymosin Alpha-1 is a unique peptide used to treat Lyme’s disease, fibromyalgia, autoimmune diseases, irritable bowel syndrome, and chronic infections like hepatitis B and hepatitis C. It’s unique in balancing the immune system.

Thymosin Beta-4

Thymosin Beta-4 is a peptide that upregulates the cellular wound healing processes and downregulates cellular oxidation and inflammation. Oxidation and inflammation impair cellular repair and stem cell regeneration.

SARMs S4 & S22

SARMs S4 and S22 are androgen receptor peptides that can bind with testosterone receptors in the body while mimicking the effect of testosterone without the unpleasant side effects. SARMs increase muscle mass and strength, promote fat loss, and increase bone density and libido.

IGF-1

IGF-1 is an essential hormone responsible for the early development of the central nervous system. IGF-1 is made in the liver in response to growth hormone signaling. The brain and spinal cord also make their own IGF-1.

Following traumatic brain injury (TBI ) there is a drop in brain and spinal cord IGF-1. Brain and spinal cord IGF-1 are hormones essential for neuroregeneration. IGF-1 is essential for synaptic function that takes place between nerve cells.

When synaptic capacity ( the way in which nerve cells communicate with one another ) is lost, that’s when cognitive function, learning and memory are lost. The peptide IGF-1 crosses the blood brain barrier where it regenerates neuronal-axonal function; the process whereby nerve cells communicate with one another once again.

IGF-1 has also been shown to be successful in treating Autism Spectrum Disorders. Additionally, its been effective in improving the symptoms of neurodegenerative disorders like Amyotrophic Lateral Sclerosis, Multiple Sclerosis and Parkinson’s disease.

Selank

Selank is a nootropic peptide improving cognition, memory, executive function and the speed of mental processes. It’s best known for its anti-anxiolytic effect; it’s comparable to Valium and Ativan, without the addictive and withdrawal consequences common with benzodiazepine use. Selank may be used to wean patients off of chronic benzodiazepine use. It’s typically given nasally. Selank is also an anti-depressant.

Semax

Is a nootropic, neuroprotective, neuroregenerative peptide used in patients following a vascular stroke, traumatic brain injury, transient ischemic attack, and those with cognitive disorders and those suffering from memory loss due to dementia and Alzheimer’s diseases.

Its typically given nasally. It’s also known to boost the immune system and restore the optic nerve, the nerve to the eye. It increases ( BDNF ) brain derived neurotrophic growth factor ( which repairs brain and spinal cord cells ). Your own brain and spinal cord cells make their own BDNF to restore neural function.

Semax prevents and reduces the neuroinflammation and neuroxidation within the central nervous that is partially responsible for the neural damage associated with traumatic brain injury (TBI).

DHH-B

It’s a highly effective anti-anxiolytic and anti-panic peptide. When you feel anxious or out of control swallow a pill of DHH-B and within about 20 minutes you will feel relaxed and calm. Its relaxing calming effect lasts about 3-hours. Your anxiety is reduced and your panic attack may be averted.

Please don’t consume alcohol when using DHH-B. If you are already on benzodiazepines adding DHH-B will add to the sedative effects that come with using benzodiazepines.

At the Sand Institute there are many more supplements available to reduce your anxiety and panic attacks, like Magnesium and Vitamin B supplements.

Epitalon

It’s an anti-aging peptide used extensively in Russia where it’s an approved peptide for anti-aging.

Its a unique peptide; it’s a synthetic pineal gland peptide which has been shown to activate telomerase and thus lengthen telomeres by 33%. Lengthening telomeres is associated with a prolonged healthy longevity in both humans and other animals.

Epitalon stimulates the production of melatonin in the pineal gland which is known to be a very potent antioxidant. It’s thought that excessive oxidation in our bodies is one of the root causes of aging. Less oxidation in our bodies, the healthier we are and thus the longer we live disease free.

Epitalon also appears to improve hormonal balance at the hypothalamic pituitary axis in our brains. Hormonal balance is thought also to slow down the aging process in humans. It’s a promising peptide, though further clinical studies in humans is warranted.

Here at the Sand Institute we have used Epitalon in combination with our lifestyle intervention protocols with much success. Our clients feel healthier and have been able to “cure” themselves of type-2 diabetes by following our healthy lifestyle interventions.

Tesofensine

Is used for weight loss for its appetite suppressant effect and happens to be an outstanding supplement at “cutting” lean bulk muscle mass just prior to a body building competition.

Tesofensine is a noradrenaline-serotonin-dopamine reuptake inhibitor. It predictably and consistently diminishes appetite. In clinical trials it’s associated with about a 16kg (40 pound) weight loss in just under 24 weeks.

When combined with additional weight loss peptides ( like AOD, MOTS-C ) at the Sand Institute it provides a valuable tool in assisting a consistent and reliable weight loss program at the Sand Institute. It’s a powerful appetite suppressant.

Tesmorelin

Is a growth hormone secretagogue. Tesmorelin increases the release of growth hormone from the pituitary. Growth hormone and IGF-1 are anabolic and thus are responsible for building muscle mass and bone growth early in life.

Growth hormone is also highly lipolytic, breaking down fat cells that have accumulated deep within the abdominal cavity. This abdominal fat is referred to as Visceral Adipose Tissue ( VAT).

Tesmorelin is highly associated with reducing and eliminating visceral adipose tissue (VAT). Visceral adipose tissue is responsible for releasing adipokines (chemicals) that are associated with the origins of the metabolic syndrome which are the harbinger of type 2 diabetes, hyperlipidemia, hypertension, cardiovascular disease, stroke and Alzheimer’s dementia.

Tesmorelin is a Peptide that is used for losing weight, building muscle mass and for “cutting” lean bulk just prior to a body building competition. It’s a remarkable peptide as it is highly associated with diminishing visceral adiposity, the fat around the belly.

If you want six-pack abs, Tesmorelin is an ideal growth hormone secretagogue to achieve muscle growth while decreasing your percentage body fat to about 10% to 15%.

When men have an accumulation of (VAT) visceral adiposity, their growth hormone levels are lower, just like their lower testosterone levels.
Visceral adiposity lowers not only growth hormone and testosterone, it also lowers thyroid hormones, LH and FSH while increasing cortisol, a glucocorticoid.

Hormonal balance is essential for a healthy longevity in BOTH men and women. Every effort should be made to lower visceral adiposity and Tesmorelin is an excellent peptide for eliminating VAT.

MK 677 ( Ibutamoren)

MK 677 is used by body builders and athletes of all sports World wise.

Ibutamoren isn’t a SARM. It isn’t a steroid either, and technically it isn’t a Peptide. It’s a growth hormone secretagogue which induces your own growth hormone secretion. It’s phenomenal at building muscle mass. It’s administered orally. If you are planning to or are already on MK 677 come by the Institute to learn more about this remarkable peptide. There are deleterious side effects associated with its use. Educate yourself.

Growth hormone is an essential hormone responsible for health, longevity, muscle growth, muscle strength, preventing muscle wasting and bone growth as well as mitochondrial energy efficiency.

MK 677 is taken orally to increase a greater secretion of your own growth hormone, IGF-1 and IGFBinding Protein #3. In response to taking MK 677 you will build muscle mass while shrinking abdominal fat mass.

It’s a remarkable orally administrated growth hormone secretagogue. It was originally studied to prevent negative nitrogen balance muscle loss in elderly men by Merck in the nineties.

Body builders and athletes in all sports build muscle consistently while consuming the right diet and macros while cycling on MK 677. If you are in a catabolic state because of surgery, excessive exercising or excessive glucocorticoid secretion, MK 677 may be of benefit in reversing your muscle loss.

MK 677 improves a positive nitrogen balance during caloric restriction. The use of MK 677 is as efficacious as recombinant GH supplementation. MK 677 is an orally administered non-peptide on par with recombination GH ( illegal ) supplementation
in he early Merck studies.

Insulin insensitivity may occur with its use. All athletes on MK 677 should be followed for elevated serum glucose levels.

AOD 9064 ( Anti-Obesity Peptide)

Is a peptide specifically for weight loss!
It’s reliable and predictable when used properly.

It is a unique growth hormone peptide designed specifically to melt away abdominal fat mass, known as visceral fat. Growth hormone is highly lipolytic; it activates lipolysis, the break down of fat cells so weight loss occurs within weeks particularly over the abdominal cavity.

AOD 9064 will NOT stimulate the production of IGF-1. It’s a remarkable peptide. It’s a modified form of the actual growth hormone molecule comprising only about 10% of the entire growth hormone molecule by weight, while retaining that portion of the entire growth hormone molecule specific for lypolysis thus its an outstanding weight loss peptide without your liver producing more IGF-1.

AOD 9064 + HA

AOD 9064 with hyaluronic acid when injected into joints has been shown in preliminary studies to repair bone, ligaments and cartilage.

Experimentally it has been shown to work even better than intra-articular injected PRP ( platelet rich plasma ).

There are currently ongoing clinical trials in humans with osteoarthritis of the knee, hip and shoulder where AOD 9064 + HA is being studied for its effects in osteoarthritis.

PEG MGF

PEG: Polyethylene Glycol
MGF: Mechano Growth Factor

PEG MGF is a synthesized mechano-growth factor. It’s unique because it repairs torn muscle extremely well through a number of anabolic processes unique to muscle cell metabolism.

Muscle cells must be repaired in order to maintain strength and muscular performance. MGF has found a home among many athletes in many sports including bodybuilding. MGF is a form of IGF-1, an isoform of IGF-1.

IGF-1 and MGF are both possible treatments for frailty syndrome, sarcopenia, and the muscle wasting syndrome that occurs from possessing a chronic disease and by living a sedentary life with muscular inactivity, particularly in the setting of malnutrition.

MGF and IGF-1 both activate myocyte mTOR which ultimately ( under muscular stretch and tension ) switches on myocyte stem cells in order to repair damaged muscle cells.

PEG MGF has been injected intramuscularly following heavy compounded squats in order to promote immediate muscle cell ( actin-myosin ) regeneration following heavy workouts.

RG3 combined with NAD+ and Methlycobalamin

RG3 is given intra-nasally in patients immediately with traumatic brain injury (TBI ) and post stroke and in patients with early to moderate Alzheimer’s disease.

RG3 has been shown clinically to alter the chronic neuro-inflammatory degenerative processes found in patients with TBI and Alzheimer’s disease.

RG3 is a powerful anti-inflammatory. It inactivates tumor necrosis factor alpha, interleukin-6 and interleukin 1-beta. All three of these chemokines are responsible for the neuro-inflammatory processes that occur in patients with following stroke, with Alzheimer’s disease and those with post traumatic brain injury.

Neuro-inflammation plays a profound role in diminishing cognitive function, memory and learning. RG3 has been shown to decrease this inflammatory process long before cognitive dysfunction ensues permanently.

Kisspeptin

Is a gonadotropin releasing peptide instructing the Leydig cells in the testes to release more testosterone.

Kisspeptin is sometimes used to increase testosterone secretion in men who suffer from hypogonadal hypogonadism, rather than to start these gentlemen on a testosterone replacement therapy program.

LGD 4033 ( Ligandrol )

LGD 4033 is a SARM, a Selective Androgen Receptor Modulator. It is NOT a Peptide. LGD 4033 builds muscle and bone and acts similarly to the androgenic effects of testosterone.

LGD 4033 not only builds muscle mass and strength, it also improves AEROBIC capacity. It’s an investigational compound used to treat sarcopenia and the frailty syndrome.

It does possess side effects; because it’s investigational there aren’t many clinical studies available to assess its risk/ benefit ratio. Because it’s a SARM many believe it doesn’t possess the same risk profile associated with testosterone replacement therapy.

Still, it has found its way into the athletic sports and bodybuilding communities because of its profound anabolic effects on muscle and bone.

Don’t purchase Ligandrol or any SARM over the Internet, chances are you aren’t purchasing the SARM you believe you are.

Stenabolic ( SR 9009 )

Stenabolic is neither a SARM or a Peptide. It’s a REV ERBA Agonist.

Its metabolic effect takes place in the mitochondria of each of your muscle cells. The mitochondrion are the “power plant” of every cell in the human body. Mitochondrial diseases are incompatible with life.

SR 9009 is an investigational drug. Very few studies exist, if any. There have been no studies performed in human trials. Its toxicology is unknown.

Anecdotal evidence would suggest it improves muscular endurance, while preserving strength and muscle mass. People have used short cycles with an improved endurance profile while running marathons and playing many sports.

It’s not wise to purchase this compound over the Internet because there isn’t any guarantee your actually purchasing SR 9009. Stenabolic is given orally. When given orally it’s not known about its bioavailability. Stop by the Institute to learn more about this interesting investigational drug.

Cardarine

Is a PPAR-delta Agonist which dramatically improves endurance and thus it has found a home in the sports performance arena.

It’s a phenomenal endurance supplement associated with a highly improved fat-burning capacity.

In mice at very large doses it was associated with cancer development. Its risk profile in humans is unknown.

Often cardarine and stenabolic are stacked together to greatly improve muscular endurance.

Creatine + Bicarbonate

The combination of creatine with Sodium Bicarbonate has been shown clinically to improve endurance when ingested about one-hour prior to your run or workout.

Collagen Peptides

Collagen peptides have been shown to reduce the ongoing damage to collagen ( ligaments, tendons, joints, meniscus, actin-myosin fibers ) during excessive aerobic and resistance training.
Typically collagen peptides are used daily, depending on how often you are at the gym and how extreme your workouts are.

Frequently Asked Questions

  • What are peptides?

    What are peptides?

    Peptides are made of short amino acid chains that can attach to receptors on the surface of your cells. Some peptides tell specific cells to produce hormones (such as testosterone, thyroid, neuropeptides in the brain, and many others) and to release them in the body.

  • Who can benefit from peptide therapy?

    Who can benefit from peptide therapy?

    People of all ages, including those between the age of 80 and 90, are capable of building lean muscle mass through nutritional support, resistance training, and peptide therapies. Without muscle mass, people can waste away and expose themselves to multiple diseases.

  • How can I maintain my results?

    How can I maintain my results?

    Eating a nutritionally healthy plant-based diet, exercising on a routine basis, reducing stress, and minimizing your exposure to environmental toxins can help you maintain your results and slow the natural aging process.

  • Is the peptide MOTS-C able to help me lose weight while building muscle mass?

    Is the peptide MOTS-C able to help me lose weight while building muscle mass?

    MOTS-C is a mitochondrial peptide. Every cell in your body contains a motor or power source called the mitochondrion. Each of your cells requires energy in order to function properly. It doesn’t matter if you are running, swimming, breathing or just relaxing each of your cells are constantly at work. The foods you consume provide the mitochondrion with the energy substrate necessary to run your body.

    MOTS-C is unique because it tells your mitochondrion to burn more free fatty acids stored in your fat cells. Fatty acids provide an enormous amount of energy to fuel your body. When you burn more free fatty acids while decreasing your caloric intake you will lose visceral fat mass over your abdomen. This is why elite marathoners may run a marathon in less than two hours. Their mitochondrion is highly efficient at burning free fatty acids.

    MOTS-C is also associated with improved muscular performance, particularly for endurance athletes running marathons and also for ultra-distance marathoners and cyclists.

    MOTS-C peptide is also unique because it “mimics” the benefits of exercising ( like building muscle and losing weight ) without having to actually exercise!

    MOTS-C may be stacked with Tesmorelin and Ipamorelin to augment your own growth hormone release. Growth hormone is a very powerful lipolytic while being converted into IGF-1 in the liver. IGF-1 works directly at the muscle cell ( myocyte ) to augment muscular growth and muscular endurance during exercise and competitions.

    Stop by the Sand Institute to learn more about MOTS-C and all the other peptides available to improve your health, longevity and muscular endurance.

  • What peptide is available at the Sand Institute to improve memory, cognition and motor strength in patients with Alzheimer’s disease, those suffering an ischemic stroke and those with traumatic brain injury following a concussion?

    What peptide is available at the Sand Institute to improve memory, cognition and motor strength in patients with Alzheimer’s disease, those suffering an ischemic stroke and those with traumatic brain injury following a concussion?

    There are a handful of peptides available to help assist the brain in regenerating itself. Cerebrolysin is a remarkable peptide. It’s effective in regenerating neural tissue in patients with Alzheimer’s disease, those individuals following ischemic stroke and in those people following a traumatic brain injury, like a concussion.

    Cerebrolysin is a remarkable peptide. It has neuroprotective, neuroregenerative and neurotrophic capabilities. It restores and regenerates neural tissue in randomized controlled trials.

    Cerebrolysin is used extensively in Europe, Russia and China to assist the brain in its capacity to regenerate itself following multiple insults.

    At the Sand Institute Dr Villarreal and Dr Sand will provide you with a program unique to your specific injury. We employ a multi modal approach. We combine with our peptide therapy a unique dietary recommendation and rehabilitation program to achieve best results for you.

  • Which body building peptides build remarkable muscle mass during my “lean” bulk building phase?

    Which body building peptides build remarkable muscle mass during my “lean” bulk building phase?

    The growth hormone secretagogues MK 677 + Ipamorelin are used for 8-weeks followed by Tesmorelin + Ipamorelin for an additional 8-weeks. This combination of peptides is outstanding for building lean muscle mass.

  • What peptides do you recommend for anti-aging benefits?

    What peptides do you recommend for anti-aging benefits?

    Many peptides are anti-aging, if I were to pick just two peptides I would chose the growth hormone secretagogue combination of CjC 1295 + Ipamorelin followed by the pineal peptide, Epitalon. The secretagogues up-regulate stem cells while promoting cellular energy efficiency. Epitalon, lengthens telomere’s by 33% and promote the release of melatonin which is a powerful anti-oxidant.

  • There are moments throughout the day I become highly anxious to the point I feel a panic attack on the horizon. Which peptide will help me with my anxieties and panic attacks?

    There are moments throughout the day I become highly anxious to the point I feel a panic attack on the horizon. Which peptide will help me with my anxieties and panic attacks?

    DHH-B, is a quick acting orally administered peptide that takes effect in less than 20 minutes with its effect lasting for about 2-3-hours. There are no known side effects. Clinically it’s as effective as a benzodiazepine without the benzodiazepine side effects.

  • Which peptides are capable of improving cognitive function, memory, focus and attention after traumatic brain injury?

    Which peptides are capable of improving cognitive function, memory, focus and attention after traumatic brain injury?

    The three peptides to consider are Cerebrolysin, Selank and Semax. All three are nootrophic, neuroprotective and neuroregenerative. Each have their own unique attributes.

  • Is there a Peptide capable of improving memory in a patient with either mild to moderately severe Alzheimer’s disease?

    Is there a Peptide capable of improving memory in a patient with either mild to moderately severe Alzheimer’s disease?

    There are many helpful peptides, if I were to chose just one it would have to be Cerebrolysin.
    It’s a remarkable peptide. Memory, learning and cognitive fidelity have all improved in patients with mild to moderately severe Alzheimer’s disease.

  • Tell me about the weight loss associated with the peptide AOD 4086?

    Tell me about the weight loss associated with the peptide AOD 4086?

    AOD stands for “Anti-Obesity Compound.”
    It’s a very “tiny” peptide representing just that portion of the “larger” growth hormone molecule responsible for just growth hormone’s lipolytic activity. Growth hormone carries out many functions. If all you want from growth hormone is just weight loss. AOD 4086 is a peptide for you.

  • How does Thymosin Beta 4 help with muscular performance and muscle growth?

    How does Thymosin Beta 4 help with muscular performance and muscle growth?

    Thymosin Beta 4 promotes muscle cell regeneration to improve muscle strength and endurance. Thymosin Beta 4 downregulates cellular oxidation and inflammation within the muscle cell itself so it may regenerate efficiently.

  • There are days my muscles are very sore when I wake up in the morning. Is there a Peptide I may use to reduce the soreness in my muscles after exercising and after I run a marathon?

    There are days my muscles are very sore when I wake up in the morning. Is there a Peptide I may use to reduce the soreness in my muscles after exercising and after I run a marathon?

    Thymosin Beta-4 is a powerful antioxidant. The soreness you are experiencing is a result of the inflammation resulting from the extensive and prolonged workouts. Recall, it’s your own innate immune system that is activated to begin the repair process of building more muscle mass. Thymosin Beta-4 even activates your own innate immune system to begin the repair process of remolding tendons, ligaments and building muscle mass.

Get In Touch

Sand Institute is here to help your Cosmetic, Antiaging and Health goals.
Contact Us

Los Angeles Office
1964 Westwood Blvd., Suite 125
Los Angeles, CA 90025
Tel: 310-340-0171

Directions to LA Office

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16415 Colorado Ave., Suite 212
Paramount, CA 90723
Tel: 562-774-2306

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